Opportunity Information: Apply for PAR 23 129

The National Institutes of Health (NIH) is soliciting applications for an R24 resource-related grant to support a Coordination Center for the Models of Infectious Disease Agent Study (MIDAS) Program. This opportunity is designed to strengthen infectious disease modeling science by creating a central hub that connects the MIDAS investigator network, helps researchers work together more effectively, and makes MIDAS research outputs easier to find, use, and build on. The grant is explicitly marked "Clinical Trial Not Allowed," meaning the funded work should not include clinical trial activities.

At its core, the Coordination Center is expected to function as the connective tissue of the MIDAS network. A major responsibility is to support collaboration across MIDAS investigators and to disseminate the products that come out of MIDAS-funded work. In practical terms, the Center is meant to help ensure that models, analytical approaches, documentation, and other network outputs do not remain siloed within individual research groups, but instead become accessible resources that can be shared, compared, reused, and improved by the broader modeling community.

Another central role of the Coordination Center is to serve as the primary repository for MIDAS-related datasets, models, and software. The opportunity emphasizes maintaining and promoting shared MIDAS resources and maximizing their utility, which typically implies not only storing materials but also curating them in ways that improve discoverability, interoperability, and long-term usability. That can include practices such as consistent metadata, version control, clear licensing and reuse terms where appropriate, user documentation, and organized access mechanisms that make it straightforward for MIDAS members (and, where permitted, others) to identify what exists and understand how to implement it correctly.

The announcement also places strong emphasis on proactive community-building and workforce development. The Coordination Center is expected to develop collaborative activities and educational opportunities that enhance the usefulness of MIDAS resources, advance the field of disease modeling, and improve training opportunities for MIDAS network members. This includes explicit attention to trainees such as graduate students and postdoctoral researchers, suggesting that workshops, tutorials, seminars, office hours, training materials, and cross-site learning opportunities are within scope, so long as they directly support the modeling mission and effective use of MIDAS resources.

In addition to coordination and resource stewardship, the opportunity allows for a limited amount of funding for the Center to conduct its own rigorous research focused on evaluation and meta-analysis of existing modeling resources and approaches. This component is aimed at helping the field learn from the body of modeling work already produced, for example by systematically assessing performance, comparing methods, identifying best practices, understanding sources of uncertainty, or synthesizing evidence across models related to disease spread and intervention strategies. The key point is that this research is framed as evaluating and integrating existing modeling resources and approaches, rather than launching unrelated new primary research agendas.

The funding opportunity is listed as PAR-23-129 under CFDA 93.859, categorized under Health, and uses the NIH grant funding instrument. The listed award ceiling is $900,000. The original closing date shown is 2023-06-15, which indicates the posted competition window for that cycle; anyone planning to apply would need to confirm current status and any reissued or successor announcements.

Eligibility is broad across U.S.-based organizations and governmental entities. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories as stated); for-profit organizations other than small businesses; small businesses; and other organizations. The announcement also highlights several categories of "other eligible applicants," including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.

Foreign participation is restricted. Non-domestic (non-U.S.) entities (foreign organizations and foreign institutions) are not eligible to apply, and non-domestic components of U.S. organizations are not eligible. In addition, foreign components as defined by the NIH Grants Policy Statement are not allowed. In effect, the Coordination Center must be led and carried out entirely within allowable domestic organizational structures, without foreign components under NIH definitions.

Overall, this grant opportunity is aimed at building and running a high-impact, service-oriented infrastructure for infectious disease modeling: a central coordination function, a well-maintained and actively promoted repository of datasets/models/software, programming that strengthens collaboration and training across the MIDAS network, and a modest but meaningful research effort focused on evaluating and synthesizing existing modeling approaches to improve how infectious disease spread and interventions are studied.

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Coordination Center for the Models of Infectious Disease Agent Study (MIDAS) Program (R24 Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859.
  • This funding opportunity was created on 2023-03-06.
  • Applicants must submit their applications by 2023-06-15. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $900,000.00 in funding.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
Apply for PAR 23 129

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Frequently Asked Questions (FAQs): NIH R24 MIDAS Coordination Center (PAR-23-129)

What is this funding opportunity?

This is a National Institutes of Health (NIH) solicitation for an R24 resource-related grant to support a Coordination Center for the Models of Infectious Disease Agent Study (MIDAS) Program. The Coordination Center is intended to strengthen infectious disease modeling by acting as a central hub for the MIDAS investigator network, improving collaboration, and making MIDAS research outputs easier to find, access, reuse, and build upon.

What is the main purpose of the MIDAS Coordination Center?

The Coordination Center is expected to function as the connective tissue of the MIDAS network. Its core purpose is to support collaboration across MIDAS investigators and to disseminate products from MIDAS-funded work so that models, analytical approaches, documentation, datasets, and software do not remain siloed within individual research groups.

What kinds of activities is the Coordination Center expected to perform?

Based on the opportunity description, the Center is expected to:

  • Coordinate and strengthen collaboration among MIDAS investigators.
  • Disseminate MIDAS products and outputs to improve access and reuse.
  • Serve as a primary repository for MIDAS-related datasets, models, and software.
  • Maintain and actively promote shared MIDAS resources to maximize their utility.
  • Develop collaborative activities and educational opportunities that advance disease modeling and improve training within the MIDAS network.
  • Conduct a limited amount of its own research focused on evaluation and meta-analysis of existing modeling resources and approaches (as allowed by the announcement).

Is this grant focused on creating new infectious disease models, or on coordinating existing work?

The emphasis is on coordination, resource stewardship, dissemination, and community-building across the MIDAS network. The opportunity also allows a limited amount of rigorous research, but that research is framed around evaluation and meta-analysis of existing MIDAS modeling resources and approaches rather than launching unrelated new primary research agendas.

What does "Clinical Trial Not Allowed" mean for applicants?

The funding opportunity is explicitly marked "Clinical Trial Not Allowed." This means the funded work should not include clinical trial activities. The Coordination Center activities should remain within the scope described (coordination, repository/resource support, training/community-building, and limited evaluation/meta-analysis research) without clinical trial components.

What is the repository role of the Coordination Center?

The announcement describes the Coordination Center as the primary repository for MIDAS-related datasets, models, and software. The intent is not only storage, but also curation and promotion of shared resources so they are discoverable, accessible, and usable over time.

What kinds of resource stewardship or curation practices are implied?

While specific technical requirements are not enumerated in the provided text, the opportunity emphasizes maximizing utility of shared resources, which typically implies practices such as consistent metadata, version control, clear documentation, licensing and reuse terms where appropriate, interoperability considerations, and organized access mechanisms so users can identify what exists and understand how to use it.

How does the Coordination Center support collaboration within MIDAS?

The Center is expected to actively connect MIDAS investigators and make it easier for researchers to work together effectively. A key objective is to reduce silos by ensuring that models, analytical approaches, documentation, datasets, and software developed through MIDAS become shared resources that can be compared, reused, and improved by others.

What kinds of training and workforce development activities are within scope?

The opportunity strongly emphasizes proactive community-building and workforce development. It explicitly points to developing collaborative activities and educational opportunities that enhance the usefulness of MIDAS resources and improve training opportunities for MIDAS network members, including trainees such as graduate students and postdoctoral researchers. Examples consistent with the description include workshops, tutorials, seminars, office hours, training materials, and cross-site learning opportunities, as long as they directly support the modeling mission and effective use of MIDAS resources.

Does the Coordination Center conduct its own research?

Yes, but only in a limited way as described. The opportunity allows a limited amount of funding for the Center to conduct rigorous research focused on evaluation and meta-analysis of existing modeling resources and approaches. The intent is to systematically assess and synthesize what has already been produced (for example, comparing methods, assessing performance, identifying best practices, understanding uncertainty, or synthesizing evidence across models).

What is the award ceiling for this opportunity?

The listed award ceiling is $900,000.

What is the program and opportunity identification information?

The funding opportunity is listed as PAR-23-129 under CFDA 93.859. It is categorized under Health and uses the NIH grant funding instrument.

Who is eligible to apply?

Eligibility is broad across U.S.-based organizations and governmental entities. Eligible applicants include (as listed in the opportunity summary):

  • State, county, and local governments
  • Special district governments
  • Independent school districts
  • Public and state-controlled institutions of higher education
  • Private institutions of higher education
  • Federally recognized tribal governments and other tribal organizations
  • Public housing authorities/Indian housing authorities
  • Nonprofits with 501(c)(3) status (excluding institutions of higher education in those nonprofit categories as stated)
  • Nonprofits without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories as stated)
  • For-profit organizations other than small businesses
  • Small businesses
  • Other organizations

Are any specific institution types explicitly highlighted as eligible?

Yes. The announcement highlights additional "other eligible applicants" categories, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.

Can foreign organizations apply?

No. Non-domestic (non-U.S.) entities (foreign organizations and foreign institutions) are not eligible to apply.

Can a U.S. organization include a foreign component in the project?

No. The opportunity states that non-domestic components of U.S. organizations are not eligible and that foreign components (as defined by the NIH Grants Policy Statement) are not allowed. In effect, the Coordination Center must be led and carried out entirely within allowable domestic organizational structures without foreign components under NIH definitions.

What does it mean that this is a "resource-related" (R24) grant in this context?

In the context provided, "resource-related" reflects that the award is intended to build and run shared infrastructure and services for the MIDAS network: coordination, a maintained repository of shared datasets/models/software, dissemination, collaboration support, and training/community activities, plus a limited evaluation/meta-analysis research component to improve use of existing modeling resources.

What is the closing date shown for this opportunity?

The original closing date shown is 2023-06-15, which reflects the posted competition window for that cycle.

If the closing date is in 2023, can organizations still apply now?

The provided information indicates the original closing date for that cycle. Anyone planning to apply would need to confirm the current status of the opportunity and whether there is a reissued or successor announcement.

What is the overall goal of this Coordination Center from a field-wide perspective?

The overall goal is to build high-impact, service-oriented infrastructure for infectious disease modeling by connecting the MIDAS investigator network, maintaining and promoting shared MIDAS resources (datasets/models/software), and offering programming that strengthens collaboration and training. The limited evaluation and meta-analysis research component is intended to help the field learn from the existing body of modeling work and improve how infectious disease spread and interventions are studied.

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