Opportunity Information: Apply for PAR 21 126
The High-End Instrumentation (HEI) Grant Program (Funding Opportunity Number PAR-21-126) is a National Institutes of Health (NIH) discretionary grant opportunity under the Department of Health and Human Services. It is designed to help groups of investigators who already hold NIH support acquire or upgrade one major piece of expensive, specialized, commercially available research equipment, or an integrated instrumentation system. A central idea of the program is shared use: the application is expected to be driven by a consortium or group of NIH-funded researchers who can clearly show that a single, high-end instrument will substantially strengthen the research capabilities of multiple projects and users, rather than serving only one lab.
The program focuses specifically on high-end instrumentation purchases or upgrades, with awards starting at a minimum of $600,001 and a maximum award amount of $2,000,000. While the instrument itself can cost more than $2,000,000 (there is no stated maximum price limit for the instrument), the NIH award will not exceed the $2,000,000 ceiling, meaning applicants may need to cover remaining costs through institutional funds, cost sharing, or other sources if the total price goes beyond the award cap. The opportunity anticipates making around 25 awards, indicating a competitive selection process.
Supported instruments span a wide range of advanced biomedical and life-science technologies. Examples explicitly highlighted include biomedical imaging systems, high-throughput robotic screening platforms, X-ray diffractometers, mass spectrometers, nuclear magnetic resonance (NMR) spectrometers, DNA and protein sequencing instruments, biosensors, electron microscopes, light microscopes, and cell sorters. The language also makes clear that these examples are not exhaustive, so other high-end, specialized instruments may be considered if they fit the program goals and are justified by strong, multi-investigator scientific needs.
In terms of eligibility, the program is open to a broad set of organizations, including public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations with 501(c)(3) status, nonprofit organizations without 501(c)(3) status (as described in the notice), and other entities as allowed under NIH policy and the specific eligibility clarifications in the announcement. The opportunity is categorized under the health funding activity area and is associated with CFDA numbers 93.351 and 93.859.
Administratively, the opportunity was created on February 8, 2021, with an original closing date of June 1, 2021. The title includes the note "S10 Clinical Trial Not Allowed," which signals that the mechanism is not intended to support clinical trials. In practical terms, applicants should frame the request around instrumentation that enables or enhances biomedical research broadly, rather than proposing a clinical trial as the primary activity supported by the award.
Overall, this HEI program is aimed at expanding access to expensive, cutting-edge research tools by funding a single major instrument purchase or upgrade that will be shared by multiple NIH-supported investigators, thereby improving institutional or regional research capacity and accelerating a range of NIH-relevant scientific projects.Apply for PAR 21 126
- The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.351, 93.859.
- This funding opportunity was created on Feb 08, 2021.
- Applicants must submit their applications by Jun 01, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $2,000,000.00 in funding.
- The number of recipients for this funding is limited to 25 candidate(s).
- Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others (see text field entitled Additional Information on Eligibility for clarification).
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| Funding Opportunity |
|---|
| Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed) Apply for PAR 21 127 Funding Number: PAR 21 127 Agency: Department of Health and Human Services, National Institutes of Health Category: Health Funding Amount: $600,000 |
| Human Immunology Project Consortium (HIPC) Coordinating Center (U01 Clinical Trial Not Allowed) Apply for RFA AI 20 080 Funding Number: RFA AI 20 080 Agency: Department of Health and Human Services, National Institutes of Health Category: Health Funding Amount: $1,200,000 |
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| Strengthening Capacity within the Zambian Ministry of Health for Health Information Systems Sustainability in Support of a Data Driven National HIV/AIDS Response under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH21 2149 Funding Number: CDC RFA GH21 2149 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
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| Strengthening Public Health Capacity, Strategic Information Systems, and Community Engagement through Cooperation and Support Services from the Joint United Nations Programme on HIV/AIDS (UNAIDS) under PEPFAR Apply for CDC RFA GH21 2120 Funding Number: CDC RFA GH21 2120 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
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